Ketamine Therapy for Postpartum Depression

As many as 1 in 7 women experience postpartum depression after giving birth. Ketamine therapy can help, so you can focus on and enjoy your new baby.

How Ketamine Treats Postpartum Depression

A 2024 study revealed that a single low-dose injection of esketamine – a ketamine derivative – immediately after childbirth reduces the risk of postpartum depression in new mothers with prenatal depression by 75%. Other studies have also shown that ketamine could be a promising treatment for PPD.

Breastfeeding and Ketamine Therapy

Though it’s deemed unlikely that low-dose ketamine treatment affects infants of breastfeeding mothers, patients who are breastfeeding should consult with their physician before opting for ketamine therapy.

Postpartum depression can be devastating for new mothers, their babies and their families. Ketamine can offer rapid relief.

What is Postpartum Depression (PPD)?

PPD is a mood disorder that can lead to major depression and other agonizing symptoms in women. Linked to the hormonal shifts that occur in a woman’s body as the result of pregnancy and childbirth, risk factors include a history of depression and mental illness, birth trauma or childhood trauma.

Signs of postpartum depression include:

Difficulty sleeping

Mood swings

Intense feelings of sadness, anger, or worthlessness

Depression and suicidal thoughts

Trouble bonding with your baby

Withdrawing from family and friends

Loss of appetite or eating much more than usual

Overwhelming tiredness or loss of energy

Restlessness

Severe anxiety and panic attacks

Thoughts of harming yourself or your baby

Recurring thoughts of death or suicide

What is Postpartum Depression (PPD)?

PPD is a mood disorder that can lead to major depression and other agonizing symptoms in women. Linked to the hormonal shifts that occur in a woman’s body as the result of pregnancy and childbirth, risk factors include a history of depression and mental illness, birth trauma or childhood trauma.

Signs of postpartum depression include:

  • Mood swings
  • Depression and suicidal thoughts
  • Trouble bonding with your baby
  • Withdrawing from family and friends
  • Restlessness
  • Recurring thoughts of death or suicide

How Is Postpartum Depression Treated?

Typically, a combination of psychotherapy, social support, and antidepressant medications helps ease difficult symptoms like extreme sadness and hopelessness. 

In cases of severe PPD, mothers may not respond to conventional treatment. They may struggle to bond with their baby or be unable to experience real joy. In these cases, ketamine may be an option.

The Treatment Process

Schedule a Free Consultation

The first step in our treatment process is a consultation! We’ll take time to understand your personal struggle and determine if ketamine might be a good option.

Begin Treatment

From the moment you step into our clinic, you’ll be welcomed with a friendly smile and a calm environment. After a quick physical exam to confirm your readiness for treatment, our staff will ensure you’re completely comfortable and at ease as we prepare to begin.

During Treatment​

Settle into a cozy reclining chair in a private room. You’ll receive an eye mask, noise-canceling headphones, and playlists for you to select music. The treatment lasts 45 minutes (IV ketamine) or 2 hours (Spravato nasal spray). A physician and nurse are on site to monitor each session.

Regular Sessions

The induction period lasts 3-4 weeks and includes 6-8 sessions. After this, we’ll work together with you and your mental health providers to create a customized maintenance plan just for you. 

Rapid Relief for Postpartum Depression

Feel better in just hours to days.

2-4 hours

until most IV ketamine patients report an improvement in their symptoms.

75%

Reduced risk of major depressive episodes with a single low dose of esketamine after childbirth, according to a clinical study.

6.7%

Mothers in the esketamine group experienced major depressive episodes after 42 days, while 25.4% did in the placebo group (in a clinical study).

What Our Patients Say​

“Dr. Cheryl Malina and her staff are kind and compassionate. They truly make sure you are comfortable and feeling good before and after your treatment.”

– Caroline A.

“Dr. Malina and the staff make the experience so calming and enjoyable. The treatment is wonderful and I highly recommend it to anyone who is struggling.”

– Meagen P.

“Caring and supportive doctors and nurses.”

– Brooke L.

FAQs

Yes, when administered under medical supervision by trained physicians, ketamine therapy is safe. At KETA Medical, our team is led by emergency medicine physicians with extensive training, ensuring that every treatment adheres to the highest standards of medical safety.

Side effects may include mild nausea, dizziness, feelings of dissociation, anxiety or increased blood pressure. These typically resolve shortly after the treatment session. Our medical team monitors patients closely to manage any side effects effectively.

Esketamine (Spravato) Nasal Spray is covered by most insurance plans. IV ketamine infusions are not typically covered.

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