If you’ve undergone treatment with Spravato (esketamine) nasal spray for treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts, you’ve hopefully experienced fast and substantial symptom relief. But maintaining this progress is just as important as achieving it.
Over time, the effects of induction Spravato sessions can lessen, making booster or maintenance sessions a vital part of your long-term mental health plan.
At Keta Medical Center, we work with you to design a personalized maintenance schedule to help you maintain your progress, prevent relapse, and ensure ongoing relief from depressive symptoms.
The purpose of this phase is to sustain the progress made during induction and optimization and reduce the likelihood of relapse. For many patients, the maintenance phase is a critical part of their treatment plan, offering ongoing support for long-term stability. Whether longer-term treatment is required depends on your specific situation, and your doctor will work with you to determine the most appropriate plan.
Clinical studies underline the value of continued Spravato use alongside an oral antidepressant for reducing relapse rates. In one study, 52% of patients achieved remission by the end of the induction phase, with 66% showing significant symptom improvement. Another clinical study showed that during the maintenance phase, patients in stable remission who continued Spravato treatment had a significantly longer time to relapse compared to those who transitioned to a placebo nasal spray.
In fact, patients receiving Spravato in the latter study had a median relapse time of 635 days, compared to just 88 days for those on placebo. These findings highlight the importance of ongoing treatment through maintenance sessions and esketamine or ketamine boosters to preserve progress and support lasting recovery.
At Keta Medical Center, we’re committed to supporting your long-term well-being through compassionate care and tailored treatment plans.
Schedule a free consultation today to find out if ketamine therapy is right for you.
Over time, the effects of induction Spravato sessions can lessen, making booster or maintenance sessions a vital part of your long-term mental health plan.
At Keta Medical Center, we work with you to design a personalized maintenance schedule to help you maintain your progress, prevent relapse, and ensure ongoing relief from depressive symptoms.
How does Spravato work?
Spravato is a prescription nasal spray used alongside an oral antidepressant to treat treatment-resistant depression. Because it’s FDA-approved, it’s covered by most insurance plans. Unlike traditional antidepressants, Spravato works by enhancing the activity of glutamate, a neurotransmitter that helps regulate mood and cognitive function. This process helps improve communication between brain cells, promoting mood stability and supporting long-term mental health. Many patients experience rapid relief from symptoms, often within hours of their first treatment.The phases in Spravato treatment
Spravato treatment is divided into distinct phases:Induction
The induction phase lasts for four weeks, with two treatment sessions each week. In this phase, the goal is to deliver rapid relief from depressive symptoms and establish a strong foundation for improvement. Many patients find that the frequent treatments during this period help “reset” their brain and initiate a positive response to the therapy.Optimization
In the second phase, which lasts approximately another four weeks, the session frequency is reduced to one per week. At the end of the optimization phase, our physicians carefully evaluate the therapeutic benefits to determine the need for continued treatment.Maintenance
After completing the induction and optimization phases, most patients enter the maintenance phase. In this phase, treatment sessions are spaced out based on each individual’s needs, with treatment usually given every one to two weeks.The purpose of this phase is to sustain the progress made during induction and optimization and reduce the likelihood of relapse. For many patients, the maintenance phase is a critical part of their treatment plan, offering ongoing support for long-term stability. Whether longer-term treatment is required depends on your specific situation, and your doctor will work with you to determine the most appropriate plan.
Why Spravato booster sessions matter for long-term success
Booster sessions play a key role in sustaining the benefits of Spravato treatment over time. Whether you’re noticing a return of symptoms or want to stay ahead with a preventative approach, these sessions can help maintain symptom relief, extend the time between relapses, and support long-term mental health.Clinical studies underline the value of continued Spravato use alongside an oral antidepressant for reducing relapse rates. In one study, 52% of patients achieved remission by the end of the induction phase, with 66% showing significant symptom improvement. Another clinical study showed that during the maintenance phase, patients in stable remission who continued Spravato treatment had a significantly longer time to relapse compared to those who transitioned to a placebo nasal spray.
In fact, patients receiving Spravato in the latter study had a median relapse time of 635 days, compared to just 88 days for those on placebo. These findings highlight the importance of ongoing treatment through maintenance sessions and esketamine or ketamine boosters to preserve progress and support lasting recovery.
Ongoing care at Keta Medical Center
Your mental health journey doesn’t end with initial treatment. Booster and maintenance sessions provide a pathway to sustained recovery and a better quality of life.At Keta Medical Center, we’re committed to supporting your long-term well-being through compassionate care and tailored treatment plans.
Schedule a free consultation today to find out if ketamine therapy is right for you.
