PRISM is a new, FDA-approved therapy designed specifically for the treatment of PTSD. Developed by the health technology company GrayMatters Health, PRISM is the first and only treatment of its kind using advanced brainwave monitoring and real-time neurofeedback to help patients gain control over their stress responses.
By working with the brain’s natural ability to adapt and rewire itself — a process called self-neuromodulation — PRISM trains patients to regulate activity in the amygdala, the area responsible for the fight-flight-freeze response. This empowers individuals to manage PTSD symptoms without medication or invasive procedures.
This cutting-edge therapy is currently available at only a handful of clinics across the U.S., and Keta Medical Center is proud to be one of them.
PRISM is specifically designed for individuals diagnosed with PTSD. If you struggle with PTSD-related symptoms such as hypervigilance, emotional dysregulation, nightmares, or intrusive thoughts, PRISM can help.
PRISM therapy leverages neurofeedback technology to help individuals train their brain to regulate stress responses. The treatment uses a non-invasive EEG headset and computer simulation to create an immersive environment where patients learn to regulate overactive brain activity in the amygdala, the area linked to PTSD symptoms.
During a PRISM session, the patient views a simulated waiting room on a computer screen. The room is crowded with agitated avatars gathered around a reception desk. Using a mental strategy — such as recalling a calming memory or imagining a peaceful experience — the patient works to make the avatars sit down and relax. As the patient successfully regulates their brain activity, the avatars begin to settle. If brain activity becomes dysregulated, the avatars will stand up and move around, providing real-time feedback.
This interactive experience gives patients a sense of agency, reinforcing their ability to actively influence their own stress responses. Over time, it rewires neural pathways, promoting greater emotional resilience and reducing PTSD symptoms.
Feel better in just hours to days.
67% of patients experience significant improvement, with over 80% improvement rates in some populations, 3 months after treatment. PRISM has shown a 32% remission rate, with over 50% in certain groups.
At Keta Medical Center, we are dedicated to providing cutting-edge mental health treatments in a safe, compassionate, and professional environment. Unlike many other clinics, our treatments are overseen by board-certified emergency medicine physicians, ensuring the highest medical standards and patient safety.
Keta Medical Center is designed with patient comfort in mind, creating a warm and supportive space for healing. We recognize the vulnerability of those seeking treatment and prioritize a personalized, physician-led approach to care.
As one of the few clinics in the U.S. offering PRISM therapy, we are proud to bring this innovative PTSD treatment to our patients, providing them with access to the latest advancements in mental health care.
“Everything about this medical office is first class. The staff is committed to helping you and your condition. I highly recommend this place!”
Many patients experience noticeable improvements within weeks of starting PRISM therapy. Long-term benefits have been observed for months after treatment ends.
PRISM is well-tolerated, with studies showing only mild and transient side effects that may include fatigue, headache, and scalp discomfort in a small percentage of patients. Most individuals complete the full treatment program without any issues.
Yes. PRISM is FDA-approved for PTSD and has undergone extensive clinical testing. It is a non-invasive, medication-free therapy that does not expose patients to thinking about their trauma during treatment.
PRISM is more advanced than traditional neurofeedback. Unlike standard neurofeedback, which provides general brainwave feedback, PRISM uses an innovative approach to specifically target the amygdala, the brain region associated with PTSD. It employs an electroencephalogram (EEG)-based neurofeedback system guided by functional magnetic resonance imaging (fMRI) data.
EEG-fMRI Pattern (EFP) Biomarker was developed when researchers conducted simultaneous EEG and fMRI recordings to capture the brain’s electrical activity alongside detailed imaging data. By applying machine learning techniques, they established a model that predicts amygdala activity—typically measured by fMRI—using EEG signals. This model is termed the EEG-fMRI Pattern (EFP) biomarker. The EFP biomarker enables real-time assessment of amygdala activity through non-invasive EEG measurements, eliminating the need for continuous fMRI scanning.
PRISM was developed by GrayMatters Health, a pioneering company specializing in brain-based treatments for mental health disorders. In a technology developed by the company, advanced neuroscience is combined with real-time neurofeedback to treat PTSD. GrayMatters Health has received multiple prestigious awards for its innovation, including the 2024 Edison Gold Award, the 2021 Nature Spinoff Prize, and recognition as one of Fast Company’s Most Innovative Companies in 2024.
If you struggle with PTSD symptoms and have not fully responded to other treatments, PRISM may be a great option. Schedule a consultation with our doctors to discuss if it’s right for you.
We know life is busy, so at Keta Medical Center, we offer evening and weekend hours to fit your schedule. Our friendly administrative staff is always available to answer your questions and address any concerns. Our goal is to support you as you embark on your mental health journey with PRISM.