Check my coverage
Book a consult

Ketamine therapy for depression

  • Physician-led care
  • IV ketamine & FDA-approved Spravato® (esketamine)
  • Insurance-covered
  • 9 locations across NYC, Westchester, Long Island & New Jersey
Book a free consultation
Call (212) 229-9274

Your healing starts today!

Ketamine therapy for depression, anxiety & PTSD

  • Physician-led care
  • IV ketamine & FDA-approved Spravato® (esketamine)
  • Insurance-covered
  • 9 locations across NYC, Westchester, Long Island & New Jersey
Book a free consultation
Call (212) 229-9274

What does it mean to shpritz your depression away?

If you’ve tried antidepressant after antidepressant and still feel stuck, Spravato offers a different path: an FDA-approved nasal spray that targets glutamate, helping your brain build new pathways out of the patterns that keep depression in place. Many patients start to feel better within days — sometimes even hours — instead of the weeks or months traditional medications can take. Each session happens in a calm, comfortable setting with doctors and nurses by your side, and most major insurance plans cover treatment.

Days, not months
Time to first symptom relief for many patients
FDA
Approved for treatment-resistant depression
In-office
Physician-supervised, calm, private setting

Care by the numbers

~70%
Clinical response

In patients with treatment-resistant depression

600+
Patients treated weekly

Across our nine clinics in New York, Long Island and New Jersey.

$0–50
Cost per treatment

What most insured patients pay out of pocket for Spravato®.

Understanding the treatment

What is Spravato?

Simple and noninvasive

Spravato (or esketamine) is an FDA-approved nasal spray that is quickly and simply administered in our clinic under physician supervision.

An innovative approach

Spravato targets different brain chemicals than antidepressants, making it effective when other treatments have failed.

Rapid relief

Many patients feel better within days or even hours, unlike traditional antidepressants that take weeks or months.

Covered by insurance

For those diagnosed with treatment-resistant depression or major depressive disorder, Spravato is often covered by insurance.

Request a free consultation
Book a free consultation
The science

How Spravato works

Spravato targets different brain chemicals than conventional antidepressants.

Traditional medications target neurotransmitters like serotonin and dopamine. Spravato, on the other hand, targets glutamate, which helps your brain create new pathways and “rewire” old patterns that keep you stuck in depression.

Traditional antidepressants
  • Serotonin
  • Dopamine
Relief in weeks to months
Spravato (esketamine)
  • Glutamate
Relief in hours to days

What to expect from your first Spravato treatment session

Before each session
  • Keep hydrated, eat healthy meals and get a good night’s sleep.
  • Avoid alcohol, marijuana or other substances in the days before your session.
  • Take time for meditation, journaling or other relaxation techniques.
  • The nurse will take your vitals and review your medical information.
During treatment
  • Settle in with music or reading to allow yourself to relax.
  • You may experience intense emotions and a dreamlike state.
  • Slight dizziness and nausea are normal and fleeting.
  • Our medical team will support you during the 2-hour session.
After treatment
  • Relax in our spa like room
  • Enjoy drinks and light refreshments from our snack bar
  • The doctor will make sure you’re ready to leave.
  • Arrange for transportation home.

Why patients choose Keta Medical Center

Evening and weekend availability

Schedule appointments at times that
work best for you.

Full insurance support

We accept most major insurance plans and handle the paperwork for you.

Safe, physician-led care

Every treatment is supervised on-site by an experienced medical doctor.

Personalized treatment plans

Your treatment is designed around your unique mental health history and needs.

Integrated mental health support

We coordinate closely with your existing providers or connect you with our in-house team if needed.

Book a free consultation
Book a free consultation

Patient stories in their own words

Dawn S.

Age: 36

Occupation: Pharmacy technician

k

When did you turn to ketamine therapy and why?

The classic anti-depressants just were not working for me. I had come to a point in my life that I was extremely depressed, and it was negatively impacting my life in personal, professional, and day-to-day life.

D
k

What differences have you noticed in your overall well-being?

I feel true joy and happiness in the simple, everyday moments. I have a positive outlook on my future, and no longer ruminate on my past. I’ve been able to become my true, authentic, real and happy kind self. My personal and professional relationships are now thriving….I feel like the old me, many years ago, before I became depressed.

D
Read more
”
“I feel true joy and happiness in the simple, everyday moments again.”
What changed
  • Greater sense of joy and emotional lightness
  • Reduced anxiety and mental rumination
  • Feeling more like herself again
  • Improved focus and ability to engage in daily life

Andrew E.

Age: 54

Occupation: Musician

k

What was going through your mind most days before treatment?

There was a lot of negativity in my day-to-day, dwelling on negative things and feeling negative about myself and feeling negative from the perspective of people outside looking in at my situation.

A
k

What’s changed for you since starting ketamine therapy?

The absence of negativity — that is by far the biggest difference in your daily experience, not having that hanging over your head all day. I would be sitting reading a book and I couldn’t even get through a page because I had these thoughts about things that happened 20 years ago… Now I’m starting to look forward to things, putting things on my calendar – having things to look forward to. That’s a huge difference.

A
Read more
”
“The absence of negativity… that is by far the biggest difference in your daily experience.”
What changed
  • Reduced rumination and dwelling on the past
  • More hopefulness about the future
  • Greater emotional relief from negativity
  • Re-engaging with music, learning, and daily life
  • Feeling accepted, comfortable, and supported

Richard S.

Age: 79

Occupation: Retired

k

How has ketamine therapy helped with long-standing mental health struggles?

I pretty much was raised thinking that everything that was wrong with me was my fault… The idea that there might be something physically off — it never came up as that. It was always my guilt, my problem. And I think ketamine really freed me from that.

R
k

Can you describe a moment when you noticed a real shift?

I was walking along the street, and I was whistling, and I wasn’t particularly going anywhere marvelous. And I was noticing the trees and stuff, and I said, ‘Oh… I think I’m happy.’ I didn’t have to feel bad about it. I didn’t have to have a purpose for it. I was just happy.

R
Read more
”
“I was pretty much raised thinking that everything that was wrong with me was my fault. Ketamine really freed me from that.”
What changed
  • Mind finally able to rest
  • Released decades of self-blame
  • Negative thoughts lost their grip
  • Began experiencing genuine joy and emotional relief again

Ellen W.

Age: 71

Occupation: Retired

k

How did you first come to try ketamine therapy?

I have major depression, and it’s hard to treat. I felt haunted all the time, and I couldn’t work myself up to get out of the slumps. But then I found out about this, and when I found out that I could do it on insurance and it was covered, I was flipping out. I said, ‘I have to try it.’

E
k

How has ketamine therapy changed your outlook on life?

My mood would stay pretty negative, and the self-talk was always very negative… After one of my sessions, I actually thought, ‘But I can make it better.’ That would never have previously occurred to me, nor would I have said it out loud.

E
Read more
”
“The voice in my head has always been really, really negative. After one of my sessions, I actually thought, ‘But I can make it better.’”
What changed
  • Negative self-talk quieted
  • Remembered feeling truly loved
  • Able to speak positively out loud
  • Something shifted after decades of medication

Ready to Sphritz your depression away?

The best way to understand whether ketamine therapy is right for your situation is to speak with one of our intake specialists. A free phone consultation is a 15 minute conversation — no commitment, no pressure, and no obligation to proceed.
Book a free consultation
Check if your insurance covers
Spravato®
Please upload a picture of the FRONT and BACK of your insurance cards. If you have Medicare, please also upload your supplemental insurance card. Note: We do not accept Medicaid.

* Required information

;